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This page contains general information about sarcoidosis – it is a good place to start if you are new to the condition. For more in depth information on specific types of sarcoidosis (e.g. affecting lungs, eyes, skin etc.) please use the menu above.

Every case of sarcoidosis is unique; you should always consult your doctor about your treatment plan. The information below is based on best practice and evidence but should not be taken as a substitute for medical advice.

Informacije na ovoj stranici sastavljene su uz pomoć stručnjaka za sarkoidozu Dr R. Coker, Respiratory Medicine, Hammersmith Hospital, London and Dr. K. BechmanDr J. Galloway, Reumatologija, bolnica Kings College, London.

Što je sarkoidoza?

Sarcoidosis is a condition where lumps called granulomas develop at different sites within the body. Granulomas are made up of clusters of cells involved in inflammation. If many granulomas form in an organ, they can prevent that organ from working properly.

Sarcoidosis can affect many different parts of the body. It often affects the lungs but can also affect the skin, eyes, joints, nervous system, heart and other parts of the body.

Please read more information on different types of sarcoidosis by selecting the relevant page from the drop-down menu under ‘Informacija’ on the menu bar above.

Tko razvija sarkoidozu?

Sarkoidoza se često pogrešno dijagnosticira kao nešto drugo i postoji neslaganje o tome koliko ljudi živi s tim stanjem. Međutim, znamo da je sarkoidoza rijetka. Većina stručnjaka slaže se da oko 1 na svakih 10.000 ljudi ima sarkoidozu u Velikoj Britaniji. Svake godine u Velikoj Britaniji dijagnosticira se sarkoidoza oko 3.000 do 4.000 ljudi.

Sarcoidosis is prevalent in both men and women as well as all major ethnicities. There has been some research suggesting that it is slightly more prevalent in women than men. Our own research agrees with that – in SarcoidosisUK’s online community survey, 69% of respondents were female and 31% were male (7,002 participants).

Sarkoidoza se može pojaviti u bilo kojoj dobi, ali obično utječe na odrasle osobe u svojim 30-im ili 40-im godinama. 4,833 osobe iz naše ankete u zajednici rekle su nam svoje godine. Podaci pokazuju da je sarkoidoza rasprostranjena u svim dobnim skupinama - 80% slučajeva je između 37 i 65 godina. Prosječno prijavljena starost bila je 50 godina.

Često citirani Američka istraživanja kaže da ljudi afričkog i skandinavskog nasljeđa imaju veće šanse za dobivanje tog stanja, što implicira genetski element.

What Causes Sarcoidosis?

The exact cause of sarcoidosis is not known. It probably involves a precise combination of genetic and environmental factors. The condition does run in some families. So far, a single factor causing sarcoidosis has not been identified.

SarcoidosisUK preuzima vodstvo u financiranju medicinskih istraživanja kako bi utvrdio uzroke i pronašao lijek. Pročitajte više o tome SarcoidosisUK Research.

A number of websites claim to understand the causes of sarcoidosis and will sell you a cure. Please always consult your doctor before considering an alternative therapy.

What Parts of the Body are Affected?

Sarkoidoza može utjecati na gotovo bilo koji dio tijela. Najčešće su uključena pluća i limfne žlijezde u grudima, što utječe na 9 od 10 bolesnika sa sarkoidozom.

Ostali dijelovi tijela koji mogu biti najčešće uključeni su koža, oči i limfne žlijezde drugdje u tijelu.

Zglobova, mišića i kosti su uključeni u 1 od 5 pacijenata. Živci i živčani sustav uključeni su u oko 1 od 20 pacijenata. Srce je uključeno u oko 1 od 50 pacijenata.

Koji su simptomi sarkoidoze?

Simptomi sarkoidoze ovise o tome koji je dio tijela zahvaćen. Mogu uključivati:

  • kašalj
  • bez daha
  • crvene ili bolne oči
  • otečene žlijezde
  • kožni osip
  • bol u zglobovima, mišićima ili kostima
  • utrnulost ili slabost lica, ruku, nogu

Patients with sarcoidosis may feel tired and lethargic (fatigued), lose weight or suffer with fevers and night sweats. 

Ponekad, simptomi sarkoidoze počinju iznenada i ne traju dugo. Kod drugih bolesnika simptomi se mogu razvijati postupno i trajati mnogo godina.

Some people don’t have any symptoms at all and are told they have sarcoidosis after having a routine chest X-ray or other investigations.

Pročitajte više o Sarcoidosis ...

Etimologija i povijest sarkoidoze

Riječ "sarkoidoza" dolazi iz grčkog sarcο- što znači "meso", sufiks - (e) Ido meaning “resembles”, and -sis, a common suffix in Greek meaning “condition”. Therefore the whole word can be translated as something like “a condition that resembles flesh”. 

Sarcoidosis was first described in 1877 by English dermatologist Dr. Jonathan Hutchinson as “a condition causing red, raised rashes on the face, arms and hands”. Between 1909 and 1910 uveitis in sarcoidosis was first described. By 1915 it was first emphasised, by Dr. Schaumann, that it was a systemic condition (affecting the whole body).

Čitaj više: Definition and history of sarcoidosis (Sharma, 2005). 

Definition of Sarcoidosis

Sarcoidosis is famously hard to define. This is partly because of how complicated the condition can be and partly because of the lack of any known cause. SarcoidosisUK’s definition is at the top of this page. Below are some other definitions to help you more easily understand and explain sarcoidosis.

Common definition (use with friends/family/employer):

Sarcoidosis is a condition that can affect any part of the body, most often the lungs. Clumps of cells called ‘granulomas’ stop the affected organ(s) working properly. There is no known cause or cure. It affects everyone differently and the symptoms depend on the organ(s) affected. In most cases, sarcoidosis can be managed by medication and goes away after a few months or years. In the long-term it can lead to serious organ damage.

Clinical definition (use with healthcare professionals):

Sarcoidosis is a systemic granulomatous disease that primarily affects the lung and lymphatic systems of the body. A diagnosis of the disorder usually requires the demonstration of typical lesions in more than one organ system and exclusion of other disorders known to cause granulomatous disease. The appropriate therapy for the disorder also has not been well defined for all patients. Most importantly, the cause of the disorder is still unknown.

(ATS, ERS and WASOG Joint Statement on Sarcoidosis, 1999)

Official definition (for legal/official purposes):

Sarcoidosis is a multisystem disorder of unknown cause characterized by the formation of immune granulomas in involved organs. The lung and the lymphatic system are predominantly affected, but virtually every organ may be involved. Other severe manifestations result from cardiac, neurological, ocular, kidney or laryngeal localizations.

(World Health Organisation, International Classification of Diseases, 11th Revision (ICD-11), June 2018)

Kako se dijagnosticira sarkoidoza?

Sarcoidosis is difficult to diagnose because the symptoms often resemble other diseases. There is no single or specific test to diagnose sarcoidosis. 

A detailed history and examination by your doctor is the most important first step in diagnosing sarcoidosis. They will determine which parts of your body may be affected.

Blood tests Your doctor may arrange blood tests to look for signs of inflammation, to check your kidney and liver function, and your calcium levels. They may also check a marker in your blood called angiotensin-converting enzyme (ACE), which is sometimes raised in patients with sarcoidosis.

Pluća If your doctor suspects your lungs may be affected, they will usually arrange a chest X-ray and breathing tests (spirometry).

skandiranje Your doctor may also arrange imaging scans (CT scan or PET CT scan) to look for other parts of your body that may be affected but might not be causing you any symptoms. The scans will look for inflammation (granulomas).

Biopsija In order to help make a definite diagnosis of sarcoidosis a sample of tissue (a biopsy) is taken from one of the areas of inflammation (granuloma) using a bronchoscopy.

As sarcoidosis can affect many different parts of the body, your doctor may ask other specialists (who specialise in the part of your body affected by sarcoidosis) to look after you as well. SarcoidosisUK has further information on all the different types of sarcoidosis, please use the menu above to find the best information for you.


Sarcoidosis gets better without treatment in most patients (around 60%). In others, the condition persists and may require some treatment.

In the minority of patients that develop a more serious form of the disease, more aggressive and prolonged treatment is sometimes required.

A much smaller proportion of patients present with life-threatening symptoms, particularly in those with pulmonary fibrosis (lung scarring) or heart or neurological involvement.

Liječenje sarkoidoze

There is currently no known cure for sarcoidosis.

Treatment is often necessary for patients whose sarcoidosis is causing severe symptoms or is preventing the affected organ(s) from functioning normally. Sometimes simple painkillers (paracetamol or non-steroidal anti-inflammatory such as ibuprofen) may help to ease the symptoms.

The drugs used to treat sarcoidosis do so by reducing inflammation in the body. These are known as immunosuppressants. The most commonly used drugs are corticosteroids. These can be taken as a tablet (prednisolone) or given at a higher dose via a vein (methylprednisone). Treatment with corticosteroids is often required for at least 6 to 24 months.

Sometimes corticosteroids may not be completely effective, or cause side effects. Other immunosuppressants may be used, either alone or in combination, to help reduce the steroid dose. These medications include Methotrexate, Azathioprine and Mycophenolate.

Kronični slučajevi sarkoidoze obično se mogu kontrolirati lijekovima. U rijetkim slučajevima, nekim pacijentima je potrebna transplantacija kisika i / ili pluća. Jednako rijetko, oštećenje srca ili blizu njega može zahtijevati pejsmejker ili druge tretmane. Drugi tretmani također mogu biti potrebni kada su oči i koža pogođeni sarkoidozom. Provjerite određene stranice pomoću gornjeg izbornika za više informacija o tretmanima za određene vrste sarkoidoze.

Zdrav život

Sometimes patients’ symptoms may suddenly get worse (‘flare-up’). This may be triggered by stress, illness or nothing recognisable. Make sure you eat healthily, pace yourself, talk to friends and family and recognise mental health problems.

Molim kontaktirajte SarcoidosisUK or your GP for further professional support.

Page last updated: August 2019. Next review: August 2021.

Povezani sadržaji iz SarcoidosisUK:

Sarkoidoza i pluća

Imate li plućni sarkoidozu? Da li sarkoidoza utječe na pluća. Kliknite ovdje da biste saznali više.

Sarkoidoza i koža

Imate li sarkoidozu kože? Erythema Nodosum, Lupus Pernio i lezije su uobičajeni znakovi. Čitaj više.

Sarkoidoza i oko

Oko polovice pacijenata sa sarkoidozom osjećaju simptome oka. Pročitajte više o tome kako sarkoidoza može utjecati na oko.

Sarkoidoza i zglobovi, mišići i kosti

Da li sarkoidoza utječe na vaše zglobove, mišiće ili kosti? Kliknite ispod kako biste pronašli više informacija.

Sarkoidoza i živčani sustav

Sarkoidoza može utjecati na živčani sustav (neurosarkoidoza). Kliknite ispod da biste pročitali više.

Sarkoidoza i Srce

Sarkoidoza može izravno i neizravno utjecati na srce kao rezultat sarkoidoze u plućima. Pročitajte više informacija ovdje.

Sarkoidoza i umor

Osjećate li umor? Pronađite simptome, liječenje i više informacija o sarkoidozi i umoru.

Imenik konzultanata

Želite li pronaći savjetnika? Koristite naš katalog i pronađite specijalistu za sarkoidozu ili kliniku u vašoj blizini.

SarcoidosisUK Podrška

Kako vas možemo podržati? Više informacija potražite u našoj službi za pomoć, grupama za podršku i online podršci.

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